The prognostic value of serum 25-hydroxyvitamin D level in patients with ST-segment elevation myocardial infarction

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Abstract

Background
Low serum level of vitamin D has been shown to be associated with cardiovascular diseases as well as the presence of diabetes, dyslipidemia, and hypertension. Vitamin D deficiency is prevalent in Egypt as well as worldwide. We aimed to assess vitamin D status in patients with acute ST-segment elevation myocardial infarction (STEMI) and its correlation with hospital length of stay, in-hospital complication, in-hospital mortality, and 6-month mortality.
Patients and methods
In a prospective study, 53 patients with acute STEMI were included. The patients' 25-hydroxyvitamin D levels (ng/ml) were determined and the associations with clinical characteristics, laboratory data, in-hospital outcomes, and 6-month mortality were investigated. The study also included 20 healthy adult volunteers.
Results
Almost 70% of the patients in the STEMI group were vitamin D deficient (<30 ng/ml). Patients with a history of hypertension had significantly lower vitamin D levels ( < 0.001). Moreover, there was a significant positive relationship between hospital length of stay and levels of vitamin D ( < 0.003). Also, hospital length of stay was significantly shorter in patients who had undergone a primary percutaneous intervention ( < 0.008).
Conclusion
Vitamin D deficiency is highly prevalent in patients with acute STEMI. Vitamin D deficiency is highly prevalent in patients with a history of hypertension. Vitamin D deficiency is associated with longer length of hospital stay.

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